Health research
NT Health clinical trials register
Active Teletrials in NT
| Study short title/ acronym | Health condition | Study full title | Link to ANZCTR/ clinicaltrials.gov | Site principal investigator | Primary site | Satellite sites |
|---|---|---|---|---|---|---|
| AGILE-Echo | Heart Failure / Valve Heart Disease | Use of Artificial intelligence-Guided echocardiography to assIst cardiovascuLar patient managEment | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=21108&isClinicalTrial=True | Dr Angus Baumann | Alice Springs Hospital | Ti Tree CHC Hermannsburg CHC Tennant Creek Hospital |
| ASCEND | Pancreatic Cancer | A Randomised, double-blinded phase II study of gemcitabine and nab-paclitaxel with CEND-1 or placebo in patients with untreated metastatic pancreatic ductal adenocarcinoma | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=382607&isReview=true | Dr Michail Charakidis | The Queen Elizabeth Hospital, SA | Royal Darwin Hospital |
| MEGA-ROX | Critical Illness / Emergency Medicine | The Mega Randomised Registry Trial Comparing Conservative vs. Liberal OXygenation Targets | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=379432&isReview=true | Dr Lewis Campbell Dr Paul Secombe | Royal Darwin Hospital | Alice Springs Hospital |
| Pre-ANVU | Vulvar cancer | Feasibility of Groin Ultrasound to Predict Groin Lymph Node Involvement in Patients with Histologically Proven Vulvar Cancer and Feasibility of biomarker discovery in the differential diagnosis of VIN versus invasive vulvar cancer | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=384233&isReview=true | Dr Michelle Harris | Royal Brisbane and Women’s Hospital | Royal Darwin Hospital |
| SELECT-SLE | Systemic Lupus Erythematosus | A Phase 3 Program to Evaluate the Safety and Efficacy of Upadacitinib in Subjects With Moderately to Severely Active SLE | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=21246&isClinicalTrial=True | Dr Ju Ann Tan | The Queen Elizabeth Hospital, SA | Royal Darwin Hospital |
| SOCRATES HCC | Early Hepatocellular Carcinoma | A randomised controlled trial of Standard Of Care versus RadioAblaTion in Early Stage HCC | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=381818&isReview=true | Dr Kirsty Campbell | Flinders Medical Centre, SA | Royal Darwin Hospital |
| TELEKINESIS | Kidney Nutrition | The Telenutrition and Kidney Health Study. A randomised controlled trial comparing the effect of providing nutrition support and advice using digital health to standard care on serum phosphate control in patients on dialysis | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=381780&isReview=true | Rachael Smalley | Alice Springs Hospital | Royal Darwin and Palmerston Hospital Tennant Creek Hospital |
| TRITON | Necrotising soft-tissue infection | A Feasibility Trial of Tranexamic Acid for Necrotising Soft-tissue Infections | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=382739&isReview=true | Dr Tejinder Mettho | Alfred Hospital, Vic | Royal Darwin Hospital |
Active clinical trials in NT
| Study short title/ acronym | Health condition | Study full title | Link to ANZCTR/ clinicaltrials.gov | Site principal investigator |
|---|---|---|---|---|
| ACT-2 | Cardiovascular/Type 2 Myocardial Infarction (MI) | The Appropriateness of Coronary investigation in myocardial injury and Type 2 myocardial infarction | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=374157&isReview=true | Dr Hussam Tayeb |
| AMLM22 (IAPC) | Acute myeloid leukaemia (AML) | The International AML Platform Consortium (IAPC) Trial | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?ACTRN=12619000248167 | Dr Sunthanthira Ramamoorthy |
| ARiSE Fluids | Septic shock | Australian Resuscitation in Sepsis Evaluation: Fluid or vasopressors in Emergency Department Sepsis | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=19156&isClinicalTrial=True | Dr Sandra Brownlea |
| ARROW | Recurrent Wheeze/ respiratory | Assessing the Reduction of Recurrent admissions with OM-85 for preschool Wheeze | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=380570&isReview=true | Dr Kathryn Roberts |
| ASCOT | COVID-19 (SARS-CoV-2) | Australasian COVID-19 Trial: A multi-centre randomised clinical trial to assess clinical, virological and immunological outcomes in patients with SARS-CoV-2 infection (COVID-19) treated with lopinavir/ritonavir and/or hydroxychloroquine compared to standard of care. | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=379542&isReview=true | Dr Jane Davies |
| ASCOLT | Colorectal Cancer | Aspirin for Dukes C and High Risk Dukes B Colorectal Cancer. An International, Multi centre, Double Blind, Randomised, Placebo Controlled Phase III Trial. | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=365996&isReview=true | Dr Narayan Karanth |
| AusHep | Chronic HBV, HCV, and HIV infections | Australian Hepatitis and risk survey in prisons | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=21244&isClinicalTrial=True | Priscilla Moore |
| Azithromycin at birth | Maternal post-natal/infant infections | Single dose azithromycin shortly before birth to reduce infection in Aboriginal mothers and babies: a randomised controlled trial | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=387234&isReview=true | Dr Peter Morris |
| BALANCE | Urinary Tract Infection/Urinary Sepsis/Bacteraemia | Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness: Randomized Controlled Trial | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=380457&isReview=true | Dr Catherine Marshall |
| BCT-CAPTURE | Advanced Breast Cancer | A phase II randomised study to evaluate alpelisib plus fulvestrant versus capecitabine in oestrogen receptor-positive, HER2-negative advanced breast cancer patients with PIK3CA mutant circulating DNA | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=377949&isReview=true | Dr Narayan Karanth |
| BEST Trial | Bone & Joint Infections | BonE and joint infections – Simplifying Treatment in children trial | https://clinicaltrials.gov/ct2/show/NCT04538053?term=NCT04538053&draw=2&rank=1 | Dr Joshua Francis |
| BETTER | Bronchiectasis | A randomised controlled trial to determine if acute respiratory exacerbations (REs) be reduced during 12 months of treatment with oral erdosteine compared to placebo (equivalent volume or capsule) given twice daily among children and adults with bronchiectasis | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=381193&isReview=true | Dr Anne Chang |
| BLIPA-Aus | Respiratory Tract Infections/Wheezing | Oral bacterial lysate to prevent persistent wheeze in infants after severe bronchiolitis; a randomised placebo-controlled trial (Bacterial Lysate in Preventing Asthma – BLIPA-Aus) | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=382889&isReview=true | Dr Gabrielle McCallum |
| BONANZA | Severe Traumatic Brain Injury | Brain Oxygen Neuromonitoring in Australia and New Zealand Assessment | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=378178&isReview=true | Dr Lewis Campbell |
| BREATH | Bronchiectasis/Respiratory | Short and long-term effects of therapeutic exercise in children with bronchiectasis: a multi-centre randomised controlled trial | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=377843&isReview=true | Kim Clayworth |
| CAC-Women Trial | Cardiovascular disease | The Coronary Artery Calcium Scoring in Women with Novel Cardiovascular Risk Factors Trial | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=382996&isReview=true | Dr Louise Maple-Brown |
| CARBUNCLE | Surgical Treatment of Carbuncle | How Deep? - A randomised controlled trial into the surgical treatment of carbuncles | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=385094&isReview=true | Dr Richard Bradbury |
| CaSP | Cancer | Cancer Screening Program. Comprehensive genomic profiling as a decision tool for targeted treatment | https://www.omico.com.au/our-programs/cancer-screening-program-casp/ | Dr Michail Charakidis |
| Deadly Ears at Discharge | Severe otitis media | A hospital-based randomised controlled trial of an additional ear and hearing assessment to inform discharge planning by a trained Aboriginal Ear Health Worker in Aboriginal children with chronic ear infection | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=382700&showOriginal=true&isReview=true | Dr Peter Morris |
| D-Kids | Acute Respiratory Infection | Vitamin D supplementation to prevent respiratory infections among Indigenous children in the Northern Territory: a randomised controlled trial | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=375278&isReview=true | Dr Peter Morris |
| DYNAMIC III | Colorectal Cancer | Circulating Tumour DNA Analysis Informing Adjuvant Chemotherapy in Stage III Colon Cancer: A Multicentre Phase II/III Randomised Controlled Study | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?ACTRN=12617001566325 | Dr Narayan Karanth |
| EMBER-4 | Breast Neoplasms | A Randomised, Open-Label, Phase 3 Study of Adjuvant Imlunestrant vs Standard Adjuvant Endocrine Therapy in Patients Who Have Previously Received 2 to 5 Years of Adjuvant Endocrine Therapy for ER+, HER2- Early Breast Cancer With an Increased Risk of Recurrence | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=20735&isClinicalTrial=True | Dr Teesha Downton |
| EN-ACT | Acute Coronary Syndromes | Exploring the utility of non-Invasive Coronary Angiography in Suspected Acute Coronary Syndromes with Low Level Troponin Elevation | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=384764&isReview=true | Dr Nadarajah Kangaharan |
| ENACT | Autism Spectrum Disorder | Environmental Enrichment for infants: parenting with Acceptance and Commitment Therapy | https://anzctr.org.au/Trial/Registration/TrialReview.aspx?id=376446 | Melissa Reid |
| ENZAMET | Prostate Cancer | Randomised phase 3 trial of enzalutamide in first line androgen deprivation therapy for metastatic prostate cancer | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=4975&isClinicalTrial=True | Dr Narayan Karanth |
| EPO-TRAUMA | Trauma | ErythroPOietin Alfa to Prevent Mortality and Reduce Severe Disability in Critically Ill TRAUMA Patients | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=19198&isClinicalTrial=True | Dr Lewis Campbell |
| FEISTY II | Trauma/ | Fibrinogen Early In Severe Trauma studY II: Fibrinogen Concentrate vs. Cryoprecipitate in Traumatic Haemorrhage: A Randomised Controlled Trial | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=21101&isClinicalTrial=True | Dr Sandra Brownlea |
| FRAIL-M | Multiple Myeloma | Frailty-stratified, randomised controlled Bayesian adaptive trial of bortezomib versus lenalidomide in transplant-ineligible myeloma (FRAIL-M) | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?ACTRN=12619001199101 | Dr Ferenc Szabo |
| GOLSEEK-1 | Large B-cell Lymphoma | A Phase 3, Multicenter, Randomised, Double-blind, Placebo-controlled Study Comparing the Efficacy and Safety of Golcadomide Plus R-CHOP Chemotherapy vs Placebo Plus R-CHOP Chemotherapy in Participants with Previously Untreated High-Risk Large B-Cell Lymphoma | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=22380&isClinicalTrial=True | Dr Kristen Estabrooks |
| Hearing for Learning | Otitis Media/Conductive Hearing Loss | The Hearing for Learning Initiative - an innovative community-based service-enhancement model to address the crisis in ear and hearing health of Aboriginal children in the Northern Territory: a Phase III stepped-wedge cluster randomised controlled trial | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=18174&isClinicalTrial=True | Prof Amanda Leach |
| HomeBase2 | Chronic Obstructive Pulmonary Disease/Respiratory | HomeBase2: An implementation trial to improve access to pulmonary rehabilitation in people with chronic obstructive pulmonary disease | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=18662&isClinicalTrial=True | Coralie Branelly |
| INFERR | Anaemia/Liver Disease/Kidney Disease | Iron infusion in Haemodialysis Study: Intravenous Iron Polymaltose for Indigenous Patients with High Ferritin Levels on Haemodialysis: A Prospective Open-Label Blinded Endpoint Randomised Controlled Trial | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=378517&isReview=true | Dr William Majoni |
| INTEGRATE IIb | Advanced Gastro-Oesophageal Cancer (AGOC) | Randomised Phase III Controlled Trials of Regorafenib containing regimens versus standard care in Refractory Advanced Gastro-Oesophageal Cancer (AGOC) | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=370302&isReview=true | Dr Narayan Karanth |
| LEAP-Cough | Chronic wet cough | Developing individualised approaches for children with chronic wet cough and bronchiectasis by pheno- and endotyping: a cohort study and RCT | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=385229&isReview=true | Dr Peter Morris |
| Librexia-Stroke | Stroke | A Phase 3, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study to Demonstrate the Efficacy and Safety of Milvexian, an Oral Factor XIa Inhibitor, for Stroke Prevention after an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=21029&isClinicalTrial=True | Dr Alvaro Cervera |
| MoST Framework - Screening | Molecular Screening/Cancer | The Cancer Molecular Screening and Therapeutics (MoST) Program – A framework protocol for multiple, parallel, signal-seeking clinical studies of novel molecularly targeted therapies for patients with advanced cancer and unmet clinical need | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=370660&isReview=true | Dr Michail Charakidis |
| MoST 6 (substudies 14-15) | Cancer/NTRK1-3 positive tumours. | Single arm, open label, signal seeking, phase IIa trial of the activity of larotrectinib in patients with advanced NTRK1-3 positive tumours. | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=377225&isReview=true | Dr Michail Charakidis |
| MoST 7 (substudies 16-18) | Advanced rare or neglected cancers | Single arm, open label, signal seeking, phase II trial of Tremelimumab in patients with tumours with advanced rare or neglected cancers | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=378934&isReview=true | Dr Michail Charakidis |
| MoST 8 (substudies 19-20 & 35-36) | Cancer/HER2 amplifications or mutations | Single arm, open label, signal seeking, phase IIa trial of the activity of Trastuzumab emtansine (T-DM1) in patients with tumours harbouring HER2 amplifications or mutations | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=378088&isReview=true | Dr Michail Charakidis |
| MoST 9 (substudies 21-22) | Cancer/HER2 amplifications or mutations | Single arm, open label, signal seeking, phase II trial of the activity of tucatinib plus trastuzumab in patients with tumours harbouring HER2 amplifications or mutations | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=379978&isReview=true | Dr Michail Charakidis |
| MoST 10 (substudies 23-24) | Cancer/amplified D-type cyclins or CDK4/6 or inactivation of CDKN2A. | Single arm, open label, signal seeking, phase II trial of the activity of Palbociclib in combination with Avelumab in patients with tumours with amplified D-type cyclins or CDK4/6 or inactivation of CDKN2A. | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=379754&isReview=true | Dr Michail Charakidis |
| MoST 12 (substudies 27-30) | Lung Cancer/Other tumours harbouring BRAF V600 mutations | Single arm, open label, phase II trial of vemurafenib and cobimetinib in patients with advanced tumours harbouring BRAF V600 mutations detected by comprehensive genomic profiling | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=379986&isReview=true | Dr Michail Charakidis |
| MoST 13 (substudy 31) | Cancer/NTRK fusions or ROS1 gene | A single-arm, open-label, phase II trial of entrectinib in patients with advanced tumours harbouring NTRK fusions or ROS1 gene rearrangements detected by comprehensive genomic profiling | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=381225&isReview=true | Dr Michail Charakidis |
| MoST 14 (substudy 32) | ALK gene alterations Non-small cell lung cancer | A Single arm, open label, phase II trial of alectinib in patients with advanced tumours harbouring ALK gene alterations detected by comprehensive genomic profiling | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=381213&isReview=true | Dr Michail Charakidis |
| MoST 17 (substudies 38-39) | Adv NSCLC harbouring MET exon 14 skipping mutations | A single arm, open label, signal-seeking, phase II, trial of tepotinib in patients with advanced non-small cell lung cancer harbouring MET exon 14 skipping mutations detected by comprehensive genomic profiling | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=381345&isReview=true | Dr Michail Charakidis |
| MoST 19 (Substudies 41-42) | Solid Tumour harbouring KRAS G12C mutation | Single arm, open label, signal-seeking phase II study of Sotorasib (AMG-510) in patients with solid tumours harbouring KRAS G12C mutation. | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=383071&isReview=true | Dr Michail Charakidis |
| My Baby’s movements | Fetal complications of pregnancy | My Baby's Movements: a stepped wedge cluster randomised control trial to raise maternal awareness of fetal movements during pregnancy | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=365867&isReview=true | Dr Sujatha Thomas |
| MYDAS-T | Myelodysplasia | MDS05: Advancing therapies in Myelodysplasia: A multi-domain platform trial for patients with myelodysplasia investigating new treatments | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=383226&isReview=true | Dr Suthanthira Ramamoorthy |
| ORVAC | Viral Gastroenteritis Due to Rotavirus | A phase IV, double blind, randomised, placebo controlled clinical trial of a third scheduled dose of RV1 rotavirus vaccine in Australian Indigenous infants to improve protection against gastroenteritis | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=7011&isClinicalTrial=True | Dr Bianca Middleton |
| PARROT | Neurological impairment/Lower respiratory tract infection | Prophylactic antibiotics to prevent recurrent lower respiratory tract infections in children with neurological impairment (PARROT) study | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=378218&isReview=true | Dr Anne Chang |
| PETAL | Acute lower respiratory infection in children | Preventing recurrent Acute Lower Respiratory infections in young Indigenous Children (PETAL) study | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=377132&isReview=true | Dr Peter Morris |
| PneuMatters | Acute Lower Respiratory Infection | Preventing early-onset pneumonia in high-risk children through maternal immunisation: a multi-centre randomized controlled trial. | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=374381&isReview=true | Dr David Simon |
| PREDICT-TBI | Traumatic Brain Injury | PREdiction and Diagnosis using Imaging and Clinical biomarkers Trial in Traumatic Brain Injury: the value of Magnetic Resonance Imaging and Artificial Intelligence | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=380619&isReview=true | Dr Lewis Campbell |
| PRIMARY-2 | Prostate Cancer | Prospective multi-centre randomised trial of the additive diagnostic value of PSMA PET in men with negative/equivocal MRI in the diagnosis of significant prostate cancer | https://clinicaltrials.gov/study/NCT05154162 | Joshua James Morigi |
| Pro-Kids | Acute Respiratory Infection | Neonatal probiotics to prevent early-onset acute respiratory infections (ARIs) in high-risk children: a multisite, double-blinded, randomised controlled trial (RCT) | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=386451&isReview=true | A/Prof Michael Binks |
| PROMPT BOLUS | Paediatric Shock, Septic | Pragmatic Paediatric Trial of Balanced versus Normal Saline Fluid in Sepsis (PROMPT BOLUS) | https://clinicaltrials.gov/ct2/show/NCT04102371?term=NCT04102371&draw=2&rank=1 | Dr Anna Lithgow |
| QASC Australasia Trial | Stroke | A cluster randomised controlled trial evaluating an implementation intervention to enhance multi-national translation of nurse-initiated protocols for fever, hyperglycaemia and swallowing management following stroke | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=383068&isReview=true | Dr Alvaro Cervera Alvarez |
| QUICKSTART | Hepatitis C | Same-visit Hepatitis C Testing and Treatment to Accelerate Cure Among People Who Inject Drugs: a Cluster Randomised Control Trial | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=20365&isClinicalTrial=True | Dr Jane Davies |
| RADAR | Hodgkin Lyphoma | A randomised phase III trial with a PET response adapted design comparing ABVD +/- ISRT with A2VD +/- ISRT in patients with previously untreated stage IA/IIA Hodgkin Lymphoma | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=19950&isClinicalTrial=True | Dr Kristen Estabrooks |
| REMAP-CAP | Community-acquired Pneumonia, Influenza, COVID-19 | Randomised, Embedded, Multifactorial, Adaptive Platform trial for Community Acquired Pneumonia | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=17743&isClinicalTrial=True | Dr Lewis Campbell |
| RENO | Rectal Cancer | A Longitudinal Cohort Study of ‘Watch and Wait’ in Complete Clinical Responders after Chemoradiotherapy for Localised Rectal Cancer | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=376810&isReview=true | Dr Narayan Karanth |
| REPEAT | Primary ciliary dyskinesia | Improving outcomes of children and young adults with primary ciliary dyskinesia: a multi-centre, double blind, double-dummy, 2x2 partial factorial, randomised controlled trial | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=377259&isReview=true | Dr Anne Chang |
| RIIS | Childhood iron deficiency anaemia | Rapid Iron Infusion Study - Rapid Ferric carboxymaltose infusion (Ferinject) for iron deficiency anaemia in Aboriginal children: a randomised controlled trial | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=373008&isReview=true | Dr Peter Morris |
| ROCKet | Chronic post-surgical pain | Reduction of Chronic Post-surgical Pain with Ketamine-ROCKet Trial - A multicentre double-blind parallel-group placebo controlled randomised trial of the effect of perioperative ketamine on the risk of development of chronic post-surgical pain | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=373323&isReview=true | Dr Elystan Hughes |
| SNAP | Staphylococcus aureus bacteraemia | The Staphylococcus aureus Network Adaptive Platform trial | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=20127&isClinicalTrial=True | Dr Jane Davies |
| SODa-BIC | Metabolic acidosis | SODium BICarbonate for Metabolic Acidosis in the Intensive Care Unit (SODa-BIC): A multicentre, randomised, double-blind clinical trial | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=380795&isReview=true | Dr Lewis Campbell |
| SPICE IV | Critically ill patients/Sedation | Early Sedation with Dexmedetomidine vs. Placebo in Older Ventilated Critically Ill Patients | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=380209&isReview=true | Dr Lewis Campbell |
| SPOC | Sepsis | Equitable access to full blood examination testing at the point-of-care in remote primary health | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=385509&isReview=true | Dr Rodney Omond |
| STARS | Breast Cancer | A randomised comparison of Anastrozole before and continued during adjuvant radiotherapy for breast cancer versus Anastrozole and subsequent anti-oestrogen therapy delayed until after radiotherapy. (STARS – Study of Anastrozole and Radiotherapy Sequencing) | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=83913&isReview=true | Dr Scott Caruthers |
| SUPER-ED | Cancer of unknown primary | Solving Unknown Primary cancER Earlier Diagnosis (SUPER-ED): A stepped wedge cluster randomised controlled trial implementing a Model of Care to support earlier diagnosis | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=384740&isReview=true | Dr Narayan Karanth |
| TEACH-PD CRCT | Kidney Disease | Targeted Education ApproaCH to Improve Peritoneal Dialysis Outcomes – Cluster Randomised Controlled Trial | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=18600&isClinicalTrial=True | Dr Vijay Karepalli |
| The National Australian HCV Point-of-Care Testing Program | Hepatitis C | The National Australian HCV Point-of-Care Testing Program: An Observational Cohort Study to Evaluate the Use of Finger-stick Point-of-care Hepatitis C Testing to Enhance Diagnosis and Treatment of HCV Infection | Study Details | The National Australian HCV Point-of-Care Testing Program | ClinicalTrials.gov | Dr Dan Wilson |
| TORPIDO 30/60 | Complications of premature newborns/ resuscitation | Targeted Oxygenation in the Respiratory care of Premature Infants at Delivery: Effects on Outcome | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=367049&isReview=true | Dr Dennis Bonney |
| VALDAC | Acute Myeloid Leukemia | A phase 2 study of venetoclax in combination with low-dose cytarabine in relapsing acute myeloid leukaemia | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=377157&isReview=true | Dr Ferenc Szabo |
| WAMM | Delayed cord clamping / Premature birth | Wait a Minute or More: A pragmatic stepped wedge cluster randomised implementation trial | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=386500&isReview=true | Dr Dennis Bonney Dr Ella Huber |
| WHEAT | Necrotising Enterocolitis | WithHolding or continuing Enteral feeds Around blood Transfusion (WHEAT) to prevent necrotising enterocolitis (NEC) in preterm infants | https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=377274 | Dr Mantho Kgosiemang |
For closed clinical trials view the list of closed clinical trials.
More information
If you have any queries in regards to any of the below clinical trials, phone NT Health Research Governance Office (RGO) on 08 8922 7561 or email nthealth.rgo@nt.gov.au.
Note: Some of the trials listed are conducted by partnering institutions. If you do not see your clinical trial listed in here, contact us.
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